プロセス開発研究 バイオ医薬品 / Process Research ＆ Development of Bio Pharmaceuticals

https : / / www.talent-book.jp / chugai-pharm / stories / 53585

TOP I 2030」の実現に向けた研究機能強化

Rocheグループを含めた国内外企業等との共同研究業務を含む）

Rocheグループの一員、グローバルトップイノベーターの一員として、国内外のステークホルダーとのコラボレーションなど、世界に向けた活躍の機会があります。

CMC開発全体のプロジェクト推進業務やサプライチェーンマネジメント業務、生産技術研究業務など、当社グループ内の多様なキャリアの機会があり、実際に多くのメンバーが幅広く活躍しています。

Background to recruitment :

Strengthening research capability to realize new growth strategy "TOP I 2030"

Description of work :

Process development research of bio pharmaceutical drug substance and related leadership role in project development (therapeutic antibodies and bio pharmaceuticals by new modalities)

Related technology development and strategy planning including joint research with Roche or other companies

Study design, data acquisition, and document preparation that meet the latest global requirement of clinical trials and new drug applications

Process scale up research and technology transfer to technical team in manufacturing sites, both domestic and global

Position Features：

Innovation in pharmaceutical technology is essential to deliver Chugai's innovative bio pharmaceuticals to patients especially because complex antibodies and new modalities are created by our own unique antibody engineering technology.

In this role :

You can make a great contribution to human health and social development as we are focused on developing innovative pharmaceutical technologies based on the state-of-the-art science and are implementing them in our products.

You can have opportunities to play a key leadership role in collaboration with global stakeholders as a member of the Roche group and one of the global top leading innovators in the industry.

You can experience variable works in the entire life cycle of bio pharmaceuticals from research early development to launch, and depending on your aptitude, you can find variable career options in addition to the bioprocess researcher. (e.g. a project leader in CMC development, a project leader in supply chain management, or a researcher in manufacturing, science and technology)

Available Positions :

Cell Line Development Research

Cell Culture Process Research

Purification Process Research 応募資格／Qualifications ＜共通＞

3年以上）

RNAデータ解析など)

3年以上）

PAT（プロセス分析技術）、フィードバック制御システム、Digital Twinなどのシミュレーションに関する知識があれば、なお望ましい

3年以上）

Mechanistic Modelingなど流体シミュレーションに関する知識があれば、なお望ましい

Common＞

Qualifications and language skills required

Master’s degree+ or equivalent

Ability to read, write and communicate in business-level Japanese and English

Desired competencies :

Take ownership and have passion in creating value from the best use of state-of-the-art science and technologies, and lead the industry as one of the top leading innovators.

Maximize value as a team through collaboration with diverse stakeholders both inside and outside the company.

Identify the essential issues of complex problems which do not have clear answer, and promptly provide the well-considered best possible solution by making full use of various perspectives and evaluation axes.

Cell Line Development Research＞

Desired experience：

Bioproduction research of recombinant proteins in the related industries or academia (3 years+ experience)

Having experience of data science is more desirable.

Desired skills / knowledge / abilities：

Knowledge in bioproduction using animal cells or microbials (e.g. molecular biology, genetic engineering, cell biology, cell engineering, or RNA-seq data analysis)

Cell culture Process Research＞

Desired experience：

Bioproduction research of recombinant proteins in the related industries or academia (3 years+ experience)

Having experience of process scale up research or technical transfer to manufacturing sites is more desirable.

Having experience of data science or modeling and simulation is more desirable.

Desired skills / knowledge / abilities：

Knowledge in bioproduction using animal cells or microbials (e.g. molecular biology, cell biology, cell metabolism, or biochemical engineering)

Having knowledge in metabolome analysis, process analytical technology (PAT), feedback control system, or digital twin simulation is more desirable.

Purification Process Research＞

Desired experience：

Bioproduction research or purification process research of recombinant proteins in the related industries or academia or experience of developing purification materials such as resins or filters (3 years+ experience)

Having experience of process scale up research or technical transfer to manufacturing sites is more desirable.

Having experience of data science or modeling and simulation is more desirable.

Desired skills / knowledge / abilities：

Knowledge in protein purification (e.g. protein science, structural biology, chemical engineering, material engineering, or bioprocess engineering)

Having knowledge in fluid simulation is more desirable (e.g. mechanistic modeling of chromatography). 待遇／Salary & Benefits 当社規定により優遇いたします

To be decided in accordance with our criteria

The notification of working conditions will be made in an electronic file.

If you apply, please understand this point.