創薬におけるバイオロジクス分析研究員 / Research Scientist - Biologics Analysis for Drug Discovery

Background to recruitment :

One of Chugai Pharmaceutical's strengths is its research on biologics, particularly antibodies that apply proprietary innovative technologies, and the functions and structures of developed molecule are becoming increasingly complex and diverse. In recent years, the development of gene delivery technologies has also been promoted as a new drug discovery modality, and the targets for development are not limited to antibodies. To create innovative ""molecules"" with novel and complex functions and structures into ""biopharmaceuticals,"" analysis of functions, including interactions, and physical properties is essential. We believe that the various analytical data we obtain can contribute to the creation of high-quality molecules at the drug discovery stage, with a view to improving the success rate in the pharmaceutical development and clinical trial stages.

Given this background, a wide range of expertise and technologies are required as analytical functions in the drug discovery field. While it is essential to consistently meet the needs of drug discovery as an analytical function, it has become increasingly important to proactively consider what kind of analytical data can contribute to drug discovery, pharmaceutical development, and clinical trials, to challenge the establishment of cutting-edge new analytical technologies, and to utilize these in drug discovery.

To realize the development of innovative pharmaceuticals that can change the lives of patients around the world, we are seeking individuals who can proactively consider, propose, and execute what they can do with their expertise and analytical skills.

Description of work :

Analytical evaluation of development molecules and establishment of new analytical techniques in the development of new biologics and new drug discovery technologies. 応募資格／Qualifications 求める経験

Required Qualifications :

Analytical evaluation and establishment of new analytical techniques in protein engineering, antibody engineering, gene delivery research, and related fields.

SPRを用いた相互作用分析や熱力学的・物理化学的な分析、HPLCを用いた物性分析、質量分析を用いた分析や、細胞イメージング、タンパク質のレオロジー分析など）、新規分析系の構築の経験がある

Preferred Knowledge and Skills :

Possesses knowledge in protein science and biophysics, and is well-versed in analytical techniques and their principles related to the evaluation of molecular functions and physical properties (e.g., interaction analysis using SPR, thermodynamic and physicochemical analysis, property analysis using HPLC, mass spectrometry-based analysis, cell imaging, rheological analysis of proteins, etc.). Has experience in establishing new analytical systems.

Can identify issues, formulate research plans to address them based on personal knowledge and literature research, and execute those plans.

Desired competencies :

Always be aware of how you can contribute to drug discovery from an analytical perspective, and be able to propose and execute analyses.

Able to execute the work and achieve a result with strong sense of ownership and responsibility without depending on the difficulty of issues

Able to expand the scope of contribution by observing the issues from higher perspective and make inclusive discussion with diverse members.

Able to contribute to increase technical capability of the entire organization by development and / or acquisition of new analytical methods, improvement of workflow, and continuous idea creation

TOEIC 730点以上）

Desired Qualifications :

Those who have a Master's degree in medicine, pharmacy, science, or engineering and preferably have a Ph.D.

Proficient English skills required (TOEIC score : 730 or above)

Position Features：

In the field of drug discovery, as analytical technology experts, we collaborate with diverse researchers to create new molecules as innovative pharmaceuticals. Analytical technologies are constantly required from the initial idea conception to the clinical trial stage of drug discovery, and the evaluation targets range from antibodies to nucleic acids. Our analytical function's strength lies in our ability to engage in drug discovery research across a wide range of areas. Furthermore, since the acquired analytical data is used to determine the development potential as an investigational drug, collaboration with the Pharmaceutical Technology Division is essential.

Visualizing and gaining a detailed understanding of the processes and behaviors of molecules with complex structures and functions as they demonstrate their pharmaceutical effects through new analytical technologies is a great source of motivation for analytical researchers in the field of biology. We believe that this deep understanding leads to ideas for future drug discovery and technological advancements.

Salary & Benefits 当社規定により優遇いたします

To be decided in accordance with our criteria

The notification of working conditions will be made in an electronic file.

If you apply, please understand this point.